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His -hydroxybutyrate level was elevated at 4.3 (normal 9%, DKA or symptoms of severe hyperglycemia such as polyuria or polydipsia).1 Doses are titrated to achieve glycemic control to target a HbA 1c level of 7.0% or less.1 In our experience, it is not uncommon for young people with T2DM to require both metformin and insulin with dose intensification over time

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Unlike the full-length growth hormone, AOD9604 retains the lipolytic (fat-mobilizing) and anti-lipogenic (fat-inhibiting) properties of hGH, while importantly lacking its proliferative effects (e.g., on glucose levels, IGF-1 production, or cell proliferation)

doi:10.3233/JAD-142814 Weiss, Jessica B et al